CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.70 | Cathepsin B; Chain A |
|
3.90.70.100 | Tymovirus endopeptidases |
Domain Context
CATH Clusters
| Superfamily | 3.90.70.100 |
| Functional Family |
Enzyme Information
| 2.7.7.48 |
RNA-directed RNA polymerase.
based on mapping to UniProt P10358
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.
|
| 2.1.1.- |
Methyltransferases.
based on mapping to UniProt P10358
|
| 3.6.4.- |
Acting on ATP; involved in cellular and subcellular movement.
based on mapping to UniProt P10358
|
| 3.4.22.- |
Cysteine endopeptidases.
based on mapping to UniProt P10358
|
UniProtKB Entries (1)
| P10358 |
POLR_TYMV
Turnip yellow mosaic virus
RNA replicase polyprotein
|
PDB Structure
| PDB | 5LWA |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A mobile loop near the active site acts as a switch between the dual activities of a viral protease/deubiquitinase.
PLoS Pathog.
|