CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family |
Enzyme Information
| 3.4.21.73 |
U-plasminogen activator.
based on mapping to UniProt P06869
Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin.
-!- Formed from the inactive precursor by action of plasmin or plasma kallikrein. -!- Differs in structure from EC 3.4.21.68, and does not bind to fibrin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.21.31 and EC 3.4.99.26.
|
UniProtKB Entries (1)
| P06869 |
UROK_MOUSE
Mus musculus
Urokinase-type plasminogen activator
|
PDB Structure
| PDB | 5LHN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Discovery of a novel conformational equilibrium in urokinase-type plasminogen activator.
Sci Rep
|