CATH Classification

Domain Context

CATH Clusters

Superfamily Rhodopsin 7-helix transmembrane proteins
Functional Family Smoothened, frizzled class receptor

Enzyme Information

UniProtKB Entries (2)

P0ABE7
C562_ECOLX
Escherichia coli
Soluble cytochrome b562
Q99835
SMO_HUMAN
Homo sapiens
Smoothened homolog

PDB Structure

PDB 5L7D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of Smoothened regulation by its extracellular domains.
Byrne, E.F., Sircar, R., Miller, P.S., Hedger, G., Luchetti, G., Nachtergaele, S., Tully, M.D., Mydock-McGrane, L., Covey, D.F., Rambo, R.P., Sansom, M.S., Newstead, S., Rohatgi, R., Siebold, C.
Nature