CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.58 | Methane Monooxygenase Hydroxylase; Chain G, domain 1 |
|
1.20.58.1880 |
Domain Context
CATH Clusters
| Superfamily | 1.20.58.1880 |
| Functional Family | REST corepressor 1 |
Enzyme Information
UniProtKB Entries (1)
| O60341 |
KDM1A_HUMAN
Homo sapiens
Lysine-specific histone demethylase 1A
|
PDB Structure
| PDB | 5L3D |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors.
Hum.Mol.Genet.
|