CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.2000 | Frizzled cysteine-rich domain |
|
1.10.2000.10 | Frizzled cysteine-rich domain |
Domain Context
CATH Clusters
| Superfamily | Frizzled cysteine-rich domain |
| Functional Family | Smoothened, frizzled class receptor |
Enzyme Information
UniProtKB Entries (1)
| Q98SW5 |
Q98SW5_XENLA
Xenopus laevis
Smoothened
|
PDB Structure
| PDB | 5KZY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Cell
|