CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family

Enzyme Information

3.5.2.6
Beta-lactamase.
based on mapping to UniProt Q47066
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

Q47066
BLT1_ECOLX
Escherichia coli
Beta-lactamase Toho-1

PDB Structure

PDB 5KSC
External Links
Method NEUTRON DIFFRACTION
Organism
Primary Citation
Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A beta-Lactamase with a Monobactam Substrate.
Vandavasi, V.G., Langan, P.S., Weiss, K.L., Parks, J.M., Cooper, J.B., Ginell, S.L., Coates, L.
Antimicrob. Agents Chemother.