CATH Classification

Domain Context

CATH Clusters

Superfamily Bira Bifunctional Protein; Domain 2
Functional Family Alanine--tRNA ligase, cytoplasmic

Enzyme Information

6.1.1.7
Alanine--tRNA ligase.
based on mapping to UniProt P49588
ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).

UniProtKB Entries (1)

P49588
SYAC_HUMAN
Homo sapiens
Alanine--tRNA ligase, cytoplasmic

PDB Structure

PDB 5KNN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Evolutionary Gain of Alanine Mischarging to Noncognate tRNAs with a G4:U69 Base Pair.
Sun, L., Gomes, A.C., He, W., Zhou, H., Wang, X., Pan, D.W., Schimmel, P., Pan, T., Yang, X.L.
J.Am.Chem.Soc.