CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.50.100
Functional Family V-type proton ATPase catalytic subunit A

Enzyme Information

7.2.2.1
Na(+)-transporting two-sector ATPase.
based on mapping to UniProt Q08636
ATP + H(2)O + n Na(+)(Side 1) = ADP + phosphate + n Na(+)(Side 2).
-!- A multisubunit ATPase transporter found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis. -!- The enzyme is similar to EC 7.1.2.2 but pumps Na(+) rather than H(+). -!- Cf. EC 7.2.2.3 and EC 7.2.2.4. -!- Formerly EC 3.6.3.15.

UniProtKB Entries (1)

Q08637
NTPB_ENTHA
Enterococcus hirae ATCC 9790
V-type sodium ATPase subunit B

PDB Structure

PDB 5KNB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of the ATP-binding and ADP-release dwells of the V1 rotary motor
Suzuki, K., Mizutani, K., Maruyama, S., Shimono, K., Imai, F.L., Muneyuki, E., Kakinuma, Y., Ishizuka-Katsura, Y., Shirouzu, M., Yokoyama, S., Yamato, I., Murata, T.
Nat Commun