CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.5 | Single alpha-helices involved in coiled-coils or other helix-helix interfaces | |
1.20.5.1160 | Vasodilator-stimulated phosphoprotein |
Domain Context
CATH Clusters
Superfamily | Vasodilator-stimulated phosphoprotein |
Functional Family |
Enzyme Information
UniProtKB Entries (2)
P09493 |
TPM1_HUMAN
Homo sapiens
Tropomyosin alpha-1 chain
|
P03069 |
GCN4_YEAST
Saccharomyces cerevisiae S288C
General control protein GCN4
|
PDB Structure
PDB | 5KHT |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural destabilization of tropomyosin induced by the cardiomyopathy-linked mutation R21H.
Protein Sci.
|