CATH Classification

Domain Context

CATH Clusters

Superfamily Decaprenyl diphosphate synthase-like
Functional Family (2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase

Enzyme Information

2.5.1.-
Transferring alkyl or aryl groups, other than methyl groups.
based on mapping to UniProt Q97SR4

UniProtKB Entries (1)

Q97SR4
ISPT_STRPN
Streptococcus pneumoniae TIGR4
Isoprenyl transferase

PDB Structure

PDB 5KH5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase.
Concha, N., Huang, J., Bai, X., Benowitz, A., Brady, P., Grady, L.C., Kryn, L.H., Holmes, D., Ingraham, K., Jin, Q., Pothier Kaushansky, L., McCloskey, L., Messer, J.A., O'Keefe, H., Patel, A., Satz, A.L., Sinnamon, R.H., Schneck, J., Skinner, S.R., Summerfield, J., Taylor, A., Taylor, J.D., Evindar, G., Stavenger, R.A.
J.Med.Chem.