CATH Domain 5kh2C00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1180	Undecaprenyl pyrophosphate synthetase
	3.40.1180.10	Decaprenyl diphosphate synthase-like

Domain Context

CATH Clusters

Superfamily	Decaprenyl diphosphate synthase-like
Functional Family	(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase

Enzyme Information

2.5.1.-

Transferring alkyl or aryl groups, other than methyl groups.

based on mapping to UniProt Q97SR4

UniProtKB Entries (1)

ISPT_STRPN

Streptococcus pneumoniae TIGR4

Isoprenyl transferase

PDB Structure

PDB	5KH2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase. Concha, N., Huang, J., Bai, X., Benowitz, A., Brady, P., Grady, L.C., Kryn, L.H., Holmes, D., Ingraham, K., Jin, Q., Pothier Kaushansky, L., McCloskey, L., Messer, J.A., O'Keefe, H., Patel, A., Satz, A.L., Sinnamon, R.H., Schneck, J., Skinner, S.R., Summerfield, J., Taylor, A., Taylor, J.D., Evindar, G., Stavenger, R.A. J.Med.Chem.