CATH Classification

Domain Context

CATH Clusters

Superfamily Dehydroquinate synthase-like - alpha domain
Functional Family Alcohol dehydrogenase, iron-dependent

Enzyme Information

1.1.3.48
3-deoxy-alpha-D-manno-octulosonate 8-oxidase.
based on mapping to UniProt Q8EEB0
3-deoxy-alpha-D-manno-octulopyranosonate + O(2) = 3,8-dideoxy-8-oxo- alpha-D-manno-octulosonate + H(2)O(2).
-!- The enzyme, characterized from the bacterium Shewanella oneidensis, is involved in the formation of 8-amino-3,8-dideoxy-alpha-D-manno- octulosonate, an aminated form of Kdo found in lipopolysaccharides of members of the Shewanella genus. -!- Cf. EC 2.6.1.109.

UniProtKB Entries (1)

Q8EEB0
KDNB_SHEON
Shewanella oneidensis MR-1
3-deoxy-alpha-D-manno-octulosonate 8-oxidase

PDB Structure

PDB 5K8C
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of KdnB and KdnA from Shewanella oneidensis: Key Enzymes in the Formation of 8-Amino-3,8-Dideoxy-d-Manno-Octulosonic Acid.
Zachman-Brockmeyer, T.R., Thoden, J.B., Holden, H.M.
Biochemistry