CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.2840 | Flavivirus RNA-directed RNA polymerase, thumb domain |
Domain Context
CATH Clusters
| Superfamily | Flavivirus RNA-directed RNA polymerase, thumb domain |
| Functional Family |
Enzyme Information
UniProtKB Entries (1)
| A0A097PIE2 |
A0A097PIE2_9FLAV
Dengue virus 2
Genome polyprotein
|
PDB Structure
| PDB | 5K5M |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.
Plos Pathog.
|