CATH Classification

Domain Context

CATH Clusters

Superfamily Neutral Protease Domain 2
Functional Family Aminopeptidase

Enzyme Information

3.4.11.-
Aminopeptidases.
based on mapping to UniProt Q6P179

UniProtKB Entries (1)

Q6P179
ERAP2_HUMAN
Homo sapiens
Endoplasmic reticulum aminopeptidase 2

PDB Structure

PDB 5K1V
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency.
Mpakali, A., Giastas, P., Deprez-Poulain, R., Papakyriakou, A., Koumantou, D., Gealageas, R., Tsoukalidou, S., Vourloumis, D., Mavridis, I.M., Stratikos, E., Saridakis, E.
ACS Med Chem Lett