1 keywords

CATH Domain 5k13A00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family

Enzyme Information

UniProtKB Entries (1)

P10276
RARA_HUMAN
Homo sapiens
Retinoic acid receptor alpha

PDB Structure

PDB 5K13
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of potent and selective retinoic acid receptor gamma (RAR gamma ) antagonists for the treatment of osteoarthritis pain using structure based drug design.
Hughes, N.E., Bleisch, T.J., Jones, S.A., Richardson, T.I., Doti, R.A., Wang, Y., Stout, S.L., Durst, G.L., Chambers, M.G., Oskins, J.L., Lin, C., Adams, L.A., Page, T.J., Barr, R.J., Zink, R.W., Osborne, H., Montrose-Rafizadeh, C., Norman, B.H.
Bioorg.Med.Chem.Lett.