CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.300 | GMP Synthetase; Chain A, domain 3 |
|
3.30.300.30 | ANL, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.300.30 |
| Functional Family | Acetyl-coenzyme A synthetase |
Enzyme Information
| 6.2.1.1 |
Acetate--CoA ligase.
based on mapping to UniProt Q8ZKF6
ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
-!- Also acts on propanoate and propenoate.
|
UniProtKB Entries (1)
| Q8ZKF6 |
ACSA_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Acetyl-coenzyme A synthetase
|
PDB Structure
| PDB | 5JRH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Cyclic AMP Inhibits the Activity and Promotes the Acetylation of Acetyl-CoA Synthetase through Competitive Binding to the ATP/AMP Pocket.
J. Biol. Chem.
|