CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.160 | 3 Solenoid |
|
2.160.20 | Pectate Lyase C-like |
|
2.160.20.80 | E3 ubiquitin-protein ligase SopA |
Domain Context
CATH Clusters
| Superfamily | E3 ubiquitin-protein ligase SopA |
| Functional Family | Synaptic vesicle glycoprotein 2C |
Enzyme Information
UniProtKB Entries (2)
| P0DPI1 |
BXA1_CLOBH
Clostridium botulinum A str. Hall
Botulinum neurotoxin type A
|
| Q496J9 |
SV2C_HUMAN
Homo sapiens
Synaptic vesicle glycoprotein 2C
|
PDB Structure
| PDB | 5JLV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol.
|