CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.420.40
Functional Family Type II pantothenate kinase

Enzyme Information

2.7.1.33
Pantothenate kinase.
based on mapping to UniProt Q8NVG0
ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.

UniProtKB Entries (1)

Q8NVG0
COAW_STAAW
Staphylococcus aureus subsp. aureus MW2
Type II pantothenate kinase

PDB Structure

PDB 5JIC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of Potent Pantothenamide Inhibitors of Staphylococcus aureus Pantothenate Kinase through a Minimal SAR Study: Inhibition Is Due to Trapping of the Product.
Hughes, S.J., Barnard, L., Mottaghi, K., Tempel, W., Antoshchenko, T., Hong, B.S., Allali-Hassani, A., Smil, D., Vedadi, M., Strauss, E., Park, H.W.
Acs Infect Dis.