1 keywords

CATH Domain 5j8rB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.190 Protein-Tyrosine Phosphatase; Chain A
Homologous Superfamily 3.90.190.10 Protein tyrosine phosphatase superfamily

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Tyrosine-protein phosphatase non-receptor type 12

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q05209
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q05209
PTN12_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 12

PDB Structure

PDB 5J8R
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure and substrate specificity of PTPN12.
Li, H., Yang, F., Liu, C., Xiao, P., Xu, Y.F., Liang, Z.L., Liu, C., Wang, H.M., Wang, W.J., Zheng, W.S., Zhang, W., Ma, X.Y., He, D.F., Song, X.Y., Cui, F.A., Xu, Z.G., Yi, F., Sun, J.P., Yu, X.
Cell Rep