1 keywords

CATH Domain 5ipfA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.2020  

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Hypoxanthine phosphoribosyltransferase

Enzyme Information

2.4.2.8
Hypoxanthine phosphoribosyltransferase.
based on mapping to UniProt P09383
IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- Guanine and 6-mercaptopurine can replace hypoxanthine.

UniProtKB Entries (1)

P09383
HPRT_SCHMA
Schistosoma mansoni
Hypoxanthine-guanine phosphoribosyltransferase

PDB Structure

PDB 5IPF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
In vitro and in vivo characterization of the multiple isoforms of Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferases.
Romanello, L., Zeraik, A.E., de Freitas Fernandes, A., Torini, J.R., Bird, L.E., Nettleship, J.E., Rada, H., Reddivari, Y., Owens, R.J., Serrao, V.H.B., DeMarco, R., Brandao-Neto, J., Pereira, H.D.
Mol. Biochem. Parasitol.