CATH Classification

Domain Context

CATH Clusters

Superfamily Endonuclease/exonuclease/phosphatase
Functional Family Tyrosyl-DNA phosphodiesterase 2

Enzyme Information

3.1.4.-
Phosphoric diester hydrolases.
based on mapping to UniProt Q9JJX7

UniProtKB Entries (1)

Q9JJX7
TYDP2_MOUSE
Mus musculus
Tyrosyl-DNA phosphodiesterase 2

PDB Structure

PDB 5INP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Schellenberg, M.J., Perera, L., Strom, C.N., Waters, C.A., Monian, B., Appel, C.D., Vilas, C.K., Williams, J.G., Ramsden, D.A., Williams, R.S.
Nucleic Acids Res.