CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.630 | Cytochrome p450 |
|
1.10.630.10 | Cytochrome P450 |
Domain Context
CATH Clusters
| Superfamily | Cytochrome P450 |
| Functional Family | Cytochrome P450 monooxygenase |
Enzyme Information
| 1.14.15.8 |
Steroid 15-beta-monooxygenase.
based on mapping to UniProt Q06069
Progesterone + 2 reduced [2Fe-2S] ferredoxin + O(2) = 15-beta- hydroxyprogesterone + 2 oxidized [2Fe-2S] ferredoxin + H(2)O.
-!- The enzyme from Bacillus megaterium hydroxylates a variety of 3-oxo- Delta-4-steroids in position 15-beta. -!- Ring A-reduced, aromatic, and 3-beta-hydroxy-Delta-4-steroids do not serve as substrates.
|
| 1.14.99.- |
Miscellaneous.
based on mapping to UniProt Q06069
|
UniProtKB Entries (1)
| Q06069 |
CPXM_BACME
Bacillus megaterium
Cytochrome P450(MEG)
|
PDB Structure
| PDB | 5IKI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of CYP106A2 in Substrate-Free and Substrate-Bound Form.
Chembiochem
|