CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease Inhibitor
Functional Family Toll-like receptor 4

Enzyme Information

UniProtKB Entries (2)

Q9QUK6
TLR4_MOUSE
Mus musculus
Toll-like receptor 4
Q4G1L2
Q4G1L2_EPTBU
Eptatretus burgeri
Variable lymphocyte receptor B

PDB Structure

PDB 5IJB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M.M., Huang, H., Shi, H., Choi, J.H., Wang, K.W., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
Proc.Natl.Acad.Sci.USA