CATH Classification

Domain Context

CATH Clusters

Superfamily 3.10.450.50
Functional Family calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1

Enzyme Information

2.7.11.17
Calcium/calmodulin-dependent protein kinase.
based on mapping to UniProt Q9UQM7
ATP + a protein = ADP + a phosphoprotein.
-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

Q9UQM7
KCC2A_HUMAN
Homo sapiens
Calcium/calmodulin-dependent protein kinase type II subunit alpha

PDB Structure

PDB 5IG3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II.
Bhattacharyya, M., Stratton, M.M., Going, C.C., McSpadden, E.D., Huang, Y., Susa, A.C., Elleman, A., Cao, Y.M., Pappireddi, N., Burkhardt, P., Gee, C.L., Barros, T., Schulman, H., Williams, E.R., Kuriyan, J.
Elife