CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family 17-beta-hydroxysteroid dehydrogenase 14

Enzyme Information

1.1.1.-
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt Q9BPX1

UniProtKB Entries (1)

Q9BPX1
DHB14_HUMAN
Homo sapiens
17-beta-hydroxysteroid dehydrogenase 14

PDB Structure

PDB 5ICS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
New Insights into Human 17 beta-Hydroxysteroid Dehydrogenase Type 14: First Crystal Structures in Complex with a Steroidal Ligand and with a Potent Nonsteroidal Inhibitor.
Bertoletti, N., Braun, F., Lepage, M., Moller, G., Adamski, J., Heine, A., Klebe, G., Marchais-Oberwinkler, S.
J.Med.Chem.