1 keywords

CATH Domain 5i5zB02

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.472 Cyclin A; domain 1
Homologous Superfamily 1.10.472.10 Cyclin-like

Domain Context

CATH Clusters

Superfamily Cyclin-like
Functional Family Putative cyclin-c

Enzyme Information

UniProtKB Entries (1)

P24863
CCNC_HUMAN
Homo sapiens
Cyclin-C

PDB Structure

PDB 5I5Z
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19.
Mallinger, A., Schiemann, K., Rink, C., Sejberg, J., Honey, M.A., Czodrowski, P., Stubbs, M., Poeschke, O., Busch, M., Schneider, R., Schwarz, D., Musil, D., Burke, R., Urbahns, K., Workman, P., Wienke, D., Clarke, P.A., Raynaud, F.I., Eccles, S.A., Esdar, C., Rohdich, F., Blagg, J.
Acs Med.Chem.Lett.