CATH Classification

Domain Context

CATH Clusters

Superfamily Helix-loop-helix DNA-binding domain
Functional Family Myc proto-oncogene protein

Enzyme Information

UniProtKB Entries (1)

P01106
MYC_HUMAN
Homo sapiens
Myc proto-oncogene protein

PDB Structure

PDB 5I50
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
Jung, L.A., Gebhardt, A., Koelmel, W., Ade, C.P., Walz, S., Kuper, J., von Eyss, B., Letschert, S., Redel, C., d'Artista, L., Biankin, A., Zender, L., Sauer, M., Wolf, E., Evan, G., Kisker, C., Eilers, M.
Oncogene