CATH Domain 5i34A01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.440	Adenylosuccinate Synthetase; Chain A, domain 1
	3.40.440.10	Adenylosuccinate Synthetase, subunit A, domain 1

Domain Context

CATH Clusters

Superfamily	Adenylosuccinate Synthetase, subunit A, domain 1
Functional Family	Adenylosuccinate synthetase, chloroplastic

Enzyme Information

UniProtKB Entries (1)

J9VI09_CRYNH

Cryptococcus neoformans var. grubii H99

Adenylosuccinate synthetase

PDB Structure

PDB	5I34
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans. Blundell, R.D., Williams, S.J., Arras, S.D., Chitty, J.L., Blake, K.L., Ericsson, D.J., Tibrewal, N., Rohr, J., Koh, Y.Q., Kappler, U., Robertson, A.A., Butler, M.S., Cooper, M.A., Kobe, B., Fraser, J.A. Acs Infect Dis.