CATH Domain 5hzxA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.79	Nucleoside Triphosphate Pyrophosphohydrolase
	3.90.79.10	Nucleoside Triphosphate Pyrophosphohydrolase

Domain Context

CATH Clusters

Superfamily	Nucleoside Triphosphate Pyrophosphohydrolase
Functional Family	7,8-dihydro-8-oxoguanine triphosphatase

Enzyme Information

UniProtKB Entries (1)

Q7ZWC3_DANRE

Danio rerio

Nudix (nucleoside diphosphate-linked moiety X)-type motif 1

PDB Structure

PDB	5HZX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Hypoxic Signaling and the Cellular Redox Tumor Environment Determine Sensitivity to MTH1 Inhibition. Brautigam, L., Pudelko, L., Jemth, A.S., Gad, H., Narwal, M., Gustafsson, R., Karsten, S., Carreras Puigvert, J., Homan, E., Berndt, C., Berglund, U.W., Stenmark, P., Helleday, T. Cancer Res.