CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside Triphosphate Pyrophosphohydrolase
Functional Family 7,8-dihydro-8-oxoguanine triphosphatase

Enzyme Information

UniProtKB Entries (1)

Q7ZWC3
Q7ZWC3_DANRE
Danio rerio
Nudix (nucleoside diphosphate-linked moiety X)-type motif 1

PDB Structure

PDB 5HZX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Hypoxic Signaling and the Cellular Redox Tumor Environment Determine Sensitivity to MTH1 Inhibition.
Brautigam, L., Pudelko, L., Jemth, A.S., Gad, H., Narwal, M., Gustafsson, R., Karsten, S., Carreras Puigvert, J., Homan, E., Berndt, C., Berglund, U.W., Stenmark, P., Helleday, T.
Cancer Res.