CATH Classification

Domain Context

CATH Clusters

Superfamily YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family Polycomb protein eed

Enzyme Information

UniProtKB Entries (1)

Q15910
EZH2_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase EZH2

PDB Structure

PDB 5HYN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Justin, N., Zhang, Y., Tarricone, C., Martin, S.R., Chen, S., Underwood, E., De Marco, V., Haire, L.F., Walker, P.A., Reinberg, D., Wilson, J.R., Gamblin, S.J.
Nat Commun