CATH Domain 5hxbB01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.130	7 Propeller
	2.130.10	Methylamine Dehydrogenase; Chain H
	2.130.10.10	YVTN repeat-like/Quinoprotein amine dehydrogenase

Domain Context

CATH Clusters

Superfamily	YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family	DNA damage-binding protein 1

Enzyme Information

UniProtKB Entries (1)

DDB1_HUMAN

Homo sapiens

DNA damage-binding protein 1

PDB Structure

PDB	5HXB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase. Matyskiela, M.E., Lu, G., Ito, T., Pagarigan, B., Lu, C.C., Miller, K., Fang, W., Wang, N.Y., Nguyen, D., Houston, J., Carmel, G., Tran, T., Riley, M., Nosaka, L., Lander, G.C., Gaidarova, S., Xu, S., Ruchelman, A.L., Handa, H., Carmichael, J., Daniel, T.O., Cathers, B.E., Lopez-Girona, A., Chamberlain, P.P. Nature