CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family LIM domain kinase 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P53667
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P23528
COF1_HUMAN
Homo sapiens
Cofilin-1

PDB Structure

PDB 5HVK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases.
Hamill, S., Lou, H.J., Turk, B.E., Boggon, T.J.
Mol.Cell