CATH Classification

Domain Context

CATH Clusters

Superfamily RutC-like
Functional Family Reactive Intermediate Deaminase A, chloroplastic

Enzyme Information

3.5.99.10
2-iminobutanoate/2-iminopropanoate deaminase.
based on mapping to UniProt Q94JQ4
(1) 2-iminobutanoate + H(2)O = 2-oxobutanoate + NH(3). (2) 2-iminopropanoate + H(2)O = pyruvate + NH(3).
-!- This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17. -!- The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates.

UniProtKB Entries (1)

Q94JQ4
RIDA_ARATH
Arabidopsis thaliana
Reactive Intermediate Deaminase A, chloroplastic

PDB Structure

PDB 5HP8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of RidA, an important enzyme for the prevention of toxic side products
Liu, X., Zeng, J., Chen, X., Xie, W.
Sci Rep