CATH Classification

Domain Context

CATH Clusters

Superfamily 5'-nuclease
Functional Family

Enzyme Information

3.1.11.3
Exodeoxyribonuclease (lambda-induced).
based on mapping to UniProt P06229
Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates.
-!- Preference for double-stranded DNA. -!- Does not attack single-strand breaks. -!- Similar enzymes: T4, T5 and T7 exonucleases, mammalian DNase IV. -!- Formerly EC 3.1.4.28.
3.1.11.-
Exodeoxyribonucleases producing 5'-phosphomonoesters.
based on mapping to UniProt P06229

UniProtKB Entries (1)

P06229
EXO5_BPT5
Escherichia virus T5
T5 flap endonuclease

PDB Structure

PDB 5HP4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Direct observation of DNA threading in flap endonuclease complexes.
AlMalki, F.A., Flemming, C.S., Zhang, J., Feng, M., Sedelnikova, S.E., Ceska, T., Rafferty, J.B., Sayers, J.R., Artymiuk, P.J.
Nat.Struct.Mol.Biol.