CATH Domain 5hmlA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1010	5'-nuclease

Domain Context

CATH Clusters

Superfamily	5'-nuclease
Functional Family

Enzyme Information

3.1.11.3	Exodeoxyribonuclease (lambda-induced). based on mapping to UniProt P06229 Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates. -!- Preference for double-stranded DNA. -!- Does not attack single-strand breaks. -!- Similar enzymes: T4, T5 and T7 exonucleases, mammalian DNase IV. -!- Formerly EC 3.1.4.28.
3.1.11.-	Exodeoxyribonucleases producing 5'-phosphomonoesters. based on mapping to UniProt P06229

UniProtKB Entries (1)

EXO5_BPT5

Escherichia virus T5

T5 flap endonuclease

PDB Structure

PDB	5HML
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Direct observation of DNA threading in flap endonuclease complexes. AlMalki, F.A., Flemming, C.S., Zhang, J., Feng, M., Sedelnikova, S.E., Ceska, T., Rafferty, J.B., Sayers, J.R., Artymiuk, P.J. Nat.Struct.Mol.Biol.