CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.90 | Cystine Knot Cytokines, subunit B |
|
2.10.90.10 | Cystine-knot cytokines |
Domain Context
CATH Clusters
| Superfamily | Cystine-knot cytokines |
| Functional Family | Gremlin |
Enzyme Information
UniProtKB Entries (2)
| O88273 |
GREM2_MOUSE
Mus musculus
Gremlin-2
|
| P43026 |
GDF5_HUMAN
Homo sapiens
Growth/differentiation factor 5
|
PDB Structure
| PDB | 5HK5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of Gremlin-2 in Complex with GDF5 Gives Insight into DAN-Family-Mediated BMP Antagonism.
Cell Rep
|