CATH Classification

Domain Context

CATH Clusters

Superfamily Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
Functional Family

Enzyme Information
Cytokinin dehydrogenase.
based on mapping to UniProt E3T1W8
N(6)-dimethylallyladenine + acceptor + H(2)O = adenine + 3-methylbut-2- enal + reduced acceptor.
-!- Converts zeatin and related cytokinins. -!- Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is a dimethylallyl or other prenyl group. -!- Although this activity was previously thought to be catalyzed by a hydrogen-peroxide-forming oxidase, this enzyme does not require oxygen for activity and does not form hydrogen peroxide. -!- 2,6-dichloroindophenol, methylene blue, nitroblue tetrazolium, phenazine methosulfate and Cu(2+) in the presence of imidazole can act as acceptors.

UniProtKB Entries (1)

Zea mays
Cytokinin dehydrogenase 4

PDB Structure

External Links
Primary Citation
Cytokinin metabolism in maize: Novel evidence of cytokinin abundance, interconversions and formation of a new trans-zeatin metabolic product with a weak anticytokinin activity.
Hluska, T., Dobrev, P.I., Tarkowska, D., Frebortova, J., Zalabak, D., Kopecny, D., Plihal, O., Kokas, F., Briozzo, P., Zatloukal, M., Motyka, V., Galuszka, P.
Plant Sci.