CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Tyrosine-protein phosphatase non-receptor type 12

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q05209
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q05209
PTN12_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 12

PDB Structure

PDB 5HDE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of PTPN12 Catalytic Domain
Dong, H., Shi, J., Li, J., Li, S.
To Be Published