CATH Classification

Domain Context

CATH Clusters

Superfamily YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family Polycomb protein eed

Enzyme Information

UniProtKB Entries (1)

O75530
EED_HUMAN
Homo sapiens
Polycomb protein EED

PDB Structure

PDB 5GSA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of
Qi, W., Zhao, K., Gu, J., Huang, Y., Wang, Y., Zhang, H., Zhang, M., Zhang, J., Yu, Z., Li, L., Teng, L., Chuai, S., Zhang, C., Zhao, M., Chan, H., Chen, Z., Fang, D., Fei, Q., Feng, L., Feng, L., Gao, Y., Ge, H., Ge, X., Li, G., Lingel, A., Lin, Y., Liu, Y., Luo, F., Shi, M., Wang, L., Wang, Z., Yu, Y., Zeng, J., Zeng, C., Zhang, L., Zhang, Q., Zhou, S., Oyang, C., Atadja, P., Li, E.
Nat. Chem. Biol.