CATH Classification

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt Q9UGL1

UniProtKB Entries (1)

Q9UGL1
KDM5B_HUMAN
Homo sapiens
Lysine-specific demethylase 5B

PDB Structure

PDB 5FZL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with 3D Fragment 3-Methyl-N-Pyridin-4-Yl-1,2-Oxazole-5-Carboxamide (N09954A) (Ligand Modelled Based on Pandda Event Map, Sgc - Diamond I04-1 Fragment Screening)
Nowak, R., Krojer, T., Johansson, C., Kupinska, K., Szykowska, A., Pearce, N., Talon, R., Collins, P., Gileadi, C., Strain-Damerell, C., Burgess-Brown, N.A., Arrowsmith, C.H., Bountra, C., Edwards, A.M., von Delft, F., Brennan, P.E., Oppermann, U.
To be Published