CATH Classification

Domain Context

CATH Clusters

Superfamily 2.10.110.20
Functional Family lysine-specific demethylase 6A isoform X2

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt O14607

UniProtKB Entries (1)

O14607
UTY_HUMAN
Homo sapiens
Histone demethylase UTY

PDB Structure

PDB 5FYM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with D-2- Hydroxyglutarate
Nowak, R., Krojer, T., Johansson, C., Gileadi, C., Kupinska, K., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U.
To be Published