CATH Classification

Domain Context

CATH Clusters

Superfamily Histone deacetylase domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

A5H660
A5H660_SCHMA
Schistosoma mansoni
Histone deacetylase 8

PDB Structure

PDB 5FUE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-Based Design and Synthesis of Novel Inhibitors Targeting Hdac8 from Schistosoma Mansoni for the Treatment of Schistosomiasis.
Heimburg, T., Chakrabarti, A., Lancelot, J., Marek, M., Melesina, J., Hauser, A.T., Shaik, T.B., Duclaud, S., Robaa, D., Erdmann, F., Schmidt, M., Romier, C., Pierce, R.J., Jung, M., Sippl, W.
J.Med.Chem.