CATH Classification

Domain Context

CATH Clusters

Superfamily Fimbrial-type adhesion domain
Functional Family Type 1 fimbrin D-mannose specific adhesin

Enzyme Information

UniProtKB Entries (1)

P08191
FIMH_ECOLI
Escherichia coli K-12
Type 1 fimbrin D-mannose specific adhesin

PDB Structure

PDB 5FS5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding.
Rabbani, S., Krammer, E.M., Roos, G., Zalewski, A., Preston, R., Eid, S., Zihlmann, P., Prevost, M., Lensink, M.F., Thompson, A., Ernst, B., Bouckaert, J.
IUCrJ