CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Calcium/calmodulin-dependent protein kinase type II subunit delta isoform 2

Enzyme Information

2.7.11.17
Calcium/calmodulin-dependent protein kinase.
based on mapping to UniProt Q00168
ATP + a protein = ADP + a phosphoprotein.
-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

Q00168
KCC2A_DROME
Drosophila melanogaster
Calcium/calmodulin-dependent protein kinase type II alpha chain

PDB Structure

PDB 5FG8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase.
Castro-Rodrigues, A.F., Zhao, Y., Fonseca, F., Gabant, G., Cadene, M., Robertson, G.A., Morais-Cabral, J.H.
J.Mol.Biol.