CATH Classification

Domain Context

CATH Clusters

Superfamily Fumarase/aspartase (C-terminal domain)
Functional Family Fumarate hydratase class II

Enzyme Information

4.2.1.2
Fumarate hydratase.
based on mapping to UniProt P9WN92
(S)-malate = fumarate + H(2)O.

UniProtKB Entries (1)

P9WN92
FUMC_MYCTO
Mycobacterium tuberculosis CDC1551
Fumarate hydratase class II

PDB Structure

PDB 5F92
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site.
Kasbekar, M., Fischer, G., Mott, B.T., Yasgar, A., Hyvonen, M., Boshoff, H.I., Abell, C., Barry, C.E., Thomas, C.J.
Proc.Natl.Acad.Sci.USA