CATH Classification

Domain Context

CATH Clusters

Superfamily Tetracycline Repressor, domain 2
Functional Family HTH-type transcriptional regulator EthR

Enzyme Information

UniProtKB Entries (1)

P9WMC1
ETHR_MYCTU
Mycobacterium tuberculosis H37Rv
HTH-type transcriptional regulator EthR

PDB Structure

PDB 5F27
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters.
Nikiforov, P.O., Surade, S., Blaszczyk, M., Delorme, V., Brodin, P., Baulard, A.R., Blundell, T.L., Abell, C.
Org.Biomol.Chem.