CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1050.10
Functional Family Glutathione S-transferase 1-1

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt Q9VG98
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

Q9VG98
GSTD2_DROME
Drosophila melanogaster
Glutathione S-transferase D2

PDB Structure

PDB 5F0G
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Characterization of a Drosophila glutathione transferase involved in isothiocyanate detoxification.
Gonzalez, D., Fraichard, S., Grassein, P., Delarue, P., Senet, P., Nicolai, A., Chavanne, E., Mucher, E., Artur, Y., Ferveur, J.F., Heydel, J.M., Briand, L., Neiers, F.
Insect Biochem. Mol. Biol.