CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase SMYD3

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q9H7B4
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

P17948
VGFR1_HUMAN
Homo sapiens
Vascular endothelial growth factor receptor 1

PDB Structure

PDB 5EX3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase
Fu, W., Liu, N., Qiao, Q., Wang, M., Min, J., Zhu, B., Xu, R.M., Yang, N.
J.Biol.Chem.