CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.190.80
Functional Family Fructose-1,6-bisphosphatase class 1

Enzyme Information

3.1.3.11
Fructose-bisphosphatase.
based on mapping to UniProt O00757
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.

UniProtKB Entries (1)

O00757
F16P2_HUMAN
Homo sapiens
Fructose-1,6-bisphosphatase isozyme 2

PDB Structure

PDB 5ET5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
T-to-R switch of muscle fructose-1,6-bisphosphatase involves fundamental changes of secondary and quaternary structure.
Barciszewski, J., Wisniewski, J., Kolodziejczyk, R., Jaskolski, M., Rakus, D., Dzugaj, A.
Acta Crystallogr D Struct Biol