CATH Classification

Domain Context

CATH Clusters

Superfamily Farnesyl Diphosphate Synthase
Functional Family

Enzyme Information

4.2.3.43
Fusicocca-2,10(14)-diene synthase.
based on mapping to UniProt A2PZA5
Geranylgeranyl diphosphate = fusicocca-2,10(14)-diene + diphosphate.
-!- A multifunctional enzyme with EC 2.5.1.29 activity.
2.5.1.29
Geranylgeranyl diphosphate synthase.
based on mapping to UniProt A2PZA5
(2E,6E)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
-!- Some forms of this enzyme will also use geranyl diphosphate and dimethylallyl diphosphate as donors; it will not use larger prenyl diphosphates as efficient donors.

UniProtKB Entries (1)

A2PZA5
FC1_PHOAM
Diaporthe amygdali
Fusicoccadiene synthase

PDB Structure

PDB 5ERM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase.
Chen, M., Chou, W.K., Toyomasu, T., Cane, D.E., Christianson, D.W.
Acs Chem.Biol.